CPCRACommunity Programs for Clinical Research on AIDS
References in periodicals archive ?
There were no personal identifiers on the self-report forms, and patients completed their forms in private and then mailed them directly to the CPCRA Statistical Center at the University of Minnesota.
Salvage therapy for both arms was more aggressive than that of the CPCRA 064 study, comprising nine drugs, including one nonnucleoside reverse transcriptase inhibitor (NNRTI), three NRTIs, two ritonavir-boosted protease inhibitors, and hydroxyurea.
A CPCRA study demonstrated that weekly doses of fluconazole can also safely prevent vaginal and esophageal candidiasis, without resulting in resistance to the drug.
The first presentation, on a study called CPCRA 064, looked at whether it was better to take a 4-month treatment interruption before switching anti-HIV treatments or to just switch treatment right away.
Cofactors associated with participant compliance in two CPCRA Trials.
* CPCRA (Spring 2002 Group Meeting of the Terry Beirn Community Programs for Clinical Research on AIDS), May 4-6, Reston, Virginia, http://www.cpcra.org
Government networks and cohorts, such as the ACTG and CPCRA, may be the best chance for the salvage community because such research networks have the ability and wherewithal to conduct these types of trials.
The study (called CPCRA 064) will use viral resistance testing to see what drugs might still work against a patient's HIV.
* Philadelphia FIGHT (http://www.fight.org) is an excellently run organization which includes: the Jonathan Lax Treatment Center, an HIV clinic for persons of all income levels; community-based clinical trials funded by the CPCRA program of the.
Department of Health and Human Services (DHHS) regulations (1989), Community Programs for Clinical Research on AIDS (CPCRA, 1992, 1996) handbooks, abstracts from the 7th International AIDS Conference (Cox & Markowitz, 1991), and a transcribed presentation containing the oral history of community-based AIDS research CABs (Abrams, 1995).
One of the largest trials in the history of any infections disease, known as the Strategies for the Management of Anti-Retroviral Therapy (SMART) study, was designed by investigators with the Community Programs for Clinical Research on AIDS (CPCRA) and will compare a strategy of delayed, episodic HIV therapy against one of immediate, uninterrupted therapy in patients who are treatment naive and treatment experienced.