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The aim of the present study was to identify risk factors for CRKP infections and predictors of mortality among KP-infected adult patients.
To identify the risk factors for CRKP infections, we conducted a retrospective case-control study at Beijing University First Hospital, China, a tertiary care teaching hospital with 1600 beds.
Prompt initiation of appropriate antibiotic therapy for CRKP infections is crucial for patient survival.
Risk factors for acquisition of CRKP colonization have been mainly assessed in studies involving adult patients and were identified as antibiotic exposure, especially carabapenem, intensive care unit stay, prolonged hospitalization, poor functional status, invasive devices.
The eight patients were aged 23-75 years and had been hospitalized at one or more of 11 different units in the hospital for a median of 18 days (range: 12-83 days) before CRKP identification.
Plasmidial DNA from CRKP was obtained from alkaline lysis and it was electroporated into an Escherichia coli Top10 (Invitrogen).
We reported the second case of a CRKP carrying the [bla.
Furthermore, few investigations have examined antimicrobial drug resistance with regard to specimen source or cross-resistance patterns among CRKP.
CRKP was more prevalent in ICU settings than in non-ICU settings (6.
A case was defined as the first detection of CRKP in a patient admitted to a hospital A unit during April 2009-February 2011.
A point prevalence survey to identify the baseline prevalence of CRKP was conducted according CDC's recommended protocol (2) in the oncology and medical/surgical units at hospital A and facilitywide at LTCF A.
CRKP is resistant to almost all available antimicrobial agents, and infections with CRKP have been associated with high rates of morbidity and mortality, particularly among persons with prolonged hospitalization and those who are critically ill and exposed to invasive devices (e.
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- CRL 2688
- CRL4(CDT2) complex