Nonsteroidal anti-inflammatory drugs (NSAIDs) have shown variable benefit in CRMO therapy and are considered the best choice for treatment.
The foremost objective of this case is to highlight the importance of combination of imaging modalities in diagnosing CRMO and to exclude the close clinical and imaging differential of infectious osteomyelitis and malignancy.
6) described a case of colchicine-responsive CRMO with Mediterranean fever (MEFV) gene mutations and implied that the MEFV gene might be associated with CRMO.
To summarize, since there is no standard specific treatment for CRMO and since CRMO has some similarities with FMF, I believe that colchicine should be considered as a priority alternative drug for the management of resistant patients before promptly starting a new and expensive treatment.
The name CRMO was derived from its radiographic appearance which is similar to osteomyelitis.
This case report focuses on CRMO of the distal tibia and highlights the importance of considering this diagnosis for chronic recurrent, lower extremity bone pain in adolescents.
ijk]: variables analizadas: CH, CRH, CB, CRB, CMS, CRMS, CMO, CRMO, DMS y DMO.
Para el CRMS se obtuvieron valores de 3,42; 3,46; 3,92 y 3,83% PV y para el CRMO se obtuvieron de: 2,88; 2,85; 3,30 y 3,18% PV, para T1, T2, T3 y T4, respectivamente.
3) In a recent published review, we evaluated articles on autoinflammatory bone diseases, and the authors proposed an algorithm for the treatment of CRMO and suggested that bisphosphonate and anti-TNF[alpha] be used as a second line of treatment in cases in which NSAIDs were unsuccessfully prescribed, especially when the spine is involved.
In addition, we want to stress the need for more randomized controlled trials to better define the most appropriate treatment for patients with CRMO.
However, consultants discovered that Cameron was suffering from CRMO
No infection was identified by lesion or blood culture, and no malignancy was detected by imaging; hence, the possibility of CRMO