CRYO-ROPCryotherapy for Retinopathy of Prematurity (ophthalmology)
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Results of US randomized clinical trial of cryotherapy for ROP (CRYO-ROP).
In the 1980s, the first clinical trial on ROP treatment (CRYO-ROP) demonstrated that treatment was highly effective (9, 10).
Another reason was the fact that "threshold disease" which was included in CRYO-ROP criteria was being used as the treatment indication in these studies.
CRYO-ROP Calismasi, erken donemde iyi sonuclar gosterse de, 10 yillik takipte gorme fonksiyonu acisindan %44 duzeyinde bir basari ortaya koymustur.
Olgu serimizdeki ortalama dogum haftasi 28,50[+ or -]2,23 olup, bu oran ETROP (25,6 hafta) ve CRYO-ROP (26,5 hafta) calismalarindakine kiyasla kucuk bir miktar daha yuksek olarak gorunmektedir.
Programs to prevent ROP-induced blindness were initiated in many countries beginning in the 1980s, when the CRYO-ROP study demonstrated the first positive results from treatment of this disease with cryotherapy (13).
Although the initial results of the Early Treatment for Retinopathy of Prematurity Cooperative Group (ET-ROP) study, published in December 2003, showed significantly better ROP outcomes than the CRYO-ROP study, after nine months of pre-threshold treatment (16), the authors of the current study, who began prospective data collection in 2002, preferred to use the classical indication for treatment (i.e., threshold ROP).
Tung, "Visual acuity at 10 years in cryotherapy for retinopathy of prematurity (CRYO-ROP) study eyes: effect of retinal residua of retinopathy of prematurity," Archives of Ophthalmology, vol.