CSF2RAColony Stimulating Factor 2 Receptor, Alpha
CSF2RAColony-Stimulating Factor Receptor Alpha Subunit (genes)
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Similarly, the expression of 18 cytokine genes (IL-7, IL-10, TNFAIP8, SPP2, TNFAIP3, IFNB, CCL19, TNFAIP8L1, IL-16, CNTF, CXCL13, TNFAIP8L3, TNFSF13B, IL-34, TGFB1, TNFAIP2, CCL3, and ADIPOQ) and 39 cytokine receptor genes (CXCR7, CSF2RA, IL-1RL1, I-L1R2, IL-17RA, IFNAR1, IL-18RAP, IL-31RA, IL-9R, IL-18R1, IL-20RB, IL-21R, IL-2RG, IL-20RA, IL-4I1, LILRB1, TLR1, IL-17REL, LILRB5, TGFBR1, TLR6, TNFRSF13B, XCR1, TLR7, TNFRSF13C, TLR15 etc.
at The Zucker Hillside Hospital (ZHH) campus of The Feinstein Institute for Medical Research, this case-control whole genome study of roughly 500,000 single nucleotide polymorphisms (SNPs) revealed that a novel locus (rs4129148) near the CSF2RA gene was significantly associated with schizophrenia.
A whole genome scan revealed a strong effect of a novel region near the CSF2RA gene, and sequencing revealed specific genetic variants in the CSF2RA and IL3RA genes associated with schizophrenia.