Caption: Figure 6 A scotopic ERG recorded to a dim flash (left column) and a bright flash (right column) in the right eye and left eye of a patient with CSNB
. An example ERG waveform produced by a healthy patient during each of these tests is also shown.
Kondo's team confirmed CSNB in the Beagles using electroretinography to measure retinal function.
All the affected Beagles showed signs characteristic of the disease, specifically Schubert-Bomschein complete CSNB, also seen in humans.
The company said that the property covers widespread occurrences of ultramafic rocks in both the Raglan Horizon and the Povungnituk Group which are known to contain nickel mineralization throughout the CSNB
The cluster includes the comprehensive files Biosis, MEDLINE, CA, and JICSTE, a database produced by the Japan Information Center of Science and Technology; and the speciality files RTECS for toxicity information, MSCS-CCOHS for material safety data sheets, CHEMLIST for references to unpublished toxicology and health reports, PHAR for new drug development news, CABA for agricultural information, FSTA for food science information, CSNB
for chemical safety news, BIOQUIP for information on biotechnology equipment, Compendex*Plus for biomedical engineering research information, and PHYTOMED for plant science information.
Condition Name Gene Location Inheritance Oculocutaneous OCA1 TYR 11q14.3 AR albinism OCA2 15q12--q13 AR OCA3 TYRP1 9p23 AR OCA4 MATP 5p13.2 AR Ocular albinism OA1 GPR143 Xp22.2 XL Aniridia AN2 PAX6 11p13 AD CSNB
CSNB1 NYX Xp11.4 XL CSNB
CSNB2 CACNA1F Xp11.23 XL Rod monochromacy ACHM2 CNGA3 2q11.2 AR Cone dystrophy 4 COD4 PDE6C 10q23.33 AR Blue cone monochromacy COD5 OPN1L/MW Xq28 XL Optic nerve hypoplasia PAX6 11p13 AD (septo-optic dysplasia) HESX1 3p14.3 AR Corneal opacity PAX6 11p13 AD PITX2 4q25 AD FOXC1 6p25.3 AD Congenital cataract PAX6 11p13 AD Leber's congenital LCA1- Various Various AD/R amaurosis 15 Idiopathic NYS1 FRMD7 Xq26.2 XL NYS5 Xp11.4 XL NYS2 6p12 AD NYS3 7p11.2 AD 18q23 AD Figure 3 Some associations of infantile nystagmus, from Lorenz and Gampe.