CT-2Cordless Telephone 2
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Preliminary data in several animal models has shown significant inhibition of restenosis when CT-2 was placed directly on the vessel at the time of surgery.
Having achieved in vitro and in vivo proof of principle in preclinical models for CT-1 and CT-2, Atlantic is now actively pursuing corporate partnerships for licensing this technology, including potential rights to all second and subsequent generation compounds.
Barnathan presented data from a series of preclinical experiments designed to test the effectiveness of oral therapy and local delivery of the highly soluble monomer cyclodextrin, CT-1, and periadventitial, outer-vessel surface therapy with the insoluble polymer cyclodextrin, CT-2, in reducing intimal thickening after angioplasty or vascular grafting.