CTCAE

AcronymDefinition
CTCAECommon Terminology Criteria for Adverse Events
References in periodicals archive ?
Gastrointestinal toxicities: Low grade (CTCAE Grade 1 or 2) nausea and vomiting may be managed with dose reduction or interruption.
Toxicity was evaluated in all patients who received at least one dose of study therapy and was graded according to the National Cancer Institute CTCAE version 4.0.
Intraoperative Type of complication (i) Bowel injury 2 (#) (ii) Lung aspiration 1 (iii) Bleeding 1 Total 4 (5.6%) Postoperative Dindo-Clavien CTCAE Type of complication (i) Abdominal wall infiltration 2 1 N/A (ii) Leucopenia 1 N/A 3 (iii) Ascites leakage 1 1 N/A (iv) Nausea/vomiting 1 2 2 (v) Hematoma, transfusion 1 2 N/A (vi) Hospital mortality 1 * 5 5 Total 7 (9.9%) (#) detected and repaired intraoperatively; * ASA IV patient, 4500 ml ascites, unrelated to procedure.
As the RTOG scale is comparable to the CTCAE 4.03 system, this finding highlights the fact that maintaining the integrity of the irradiated skin with either mechanical protection or pharmacological properties of an extract, such as CSNF, may prevent damage of the basal skin layer [16].
CTCAE has graded thrombocytopenia into 4 levels [15]: grade 1 (75000 to 150,000 cells/mm3) grade 2 (50000-75000 cells/mm3), grade 3 (25000-50000 cells/mm3), and grade 4 (less than 25000/mm3).
The Common Terminology Criteria for Adverse Events (CTCAE) version 4.0 was used to grade radiation-associated toxicity [18].
The severity of atopic rash was measured by using the National Cancer Institute Common Terminology Criteria for Adverse Events version 3.0 (NCI CTCAE v3.0) (grades 1-5) [43].
The patient presented acute grade I radiodermatitis (NCI CTCAE Version 4.03) which resolved spontaneously.
However, due to their immunologic effects, there have been a number of reported toxicities termed as immune-related adverse events (irAEs), classified and graded by the National Cancer Institute clinical terminology criteria of adverse events (CTCAE).
During this treatment, the myelosuppression was mild; grade 2 anemia, grade 1 neutrophil count decreased, and grade 1 platelet count decreased, according to Common Terminology Criteria for Adverse Events (CTCAE) Version 5.0.
Unfortunately, the patient developed severe myelosuppression CTCAE grade 4, requiring several transfusions of erythrocytes and platelets, as well as the application of G-CSF.
Studies suggest CTCAE as a valid source of information in addition to clinical data for detection of chemotherapy toxicity (14,15).