CTIBLCancer Treatment-Induced Bone Loss
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In conjunction with pharmacological interventions for CTIBL, patients should try to follow general lifestyle-related guidelines for the prevention of osteoporosis.
Treatment for CTIBL in prostate cancer: current options and new horizons
Bisphosphonates (BPs) are often used for patients with bone metastases to prevent pathologic fractures, reduce bone pain or control hypercalcaemia, but they are not specifically indicated for the prevention and treatment of CTIBL. Numerous randomized controlled trials have explored the effects of BPs on BMD in the setting of ADT for nonmetastatic prostate cancer (Table 2),[sup.21]-[sup.34] but to date none have had sufficient power to demonstrate a reduction in fractures.