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References in periodicals archive ?
Furthermore, the challenge of identifying true associations between CysC and sleep disturbances in the early PD patients related to multiple comorbidities that may confound or modify hypothesized associations.
CysC inhibits cysteine proteinase, a proteolytic lysosomal enzyme that prevents bone resorption.
The preserved material was used to determine the concentrations of transferrin, IgG, KIM-1, and uromodulin (uUMOD) in urine and NGAL, CysC, and uromodulin (sUMOD) in serum.
Soomro, and Professor Liu Yang, Director General CYSC.
However, while the highest values (up to 5.31 ug/L) were in patients with the lowest eGFR, there was no significant correlation between the CysC eGFR and the level (Spearman r=-0.12, Figure 1).
To overcome these limitations, we used fully documented assays, and commutable materials with target values determined using a candidate reference measurement procedure (RMP) (9, 10) to evaluate the analytical performance of most of the available assays for CysC. Standard and expanded uncertainties were calculated by considering the uncertainties associated with bias and random effects (imprecision).
eGFR category, GFR estimating equation, n (%) mL/min/1.73 [m.sup.2] BIS1 [] [greater than or 159 (12.3) 622 (48.3) equal to] 75 60 to <75 495 (38.4) 358 (27.8) 45 to <60 481 (37.3) 209 (16.2) <45 154 (12.0) 100 (7.8) eGFR category, GFR estimating equation, n (%) mL/min/1.73 [m.sup.2] BIS2 [,cysc] [greater than or 182 (14.1) 432 (33.5) equal to] 75 60 to <75 498 (38.6) 430 (33.4) 45 to <60 485 (37.6) 284 (22.0) <45 124 (9.6) 143 (11.1) eGFR, estimated glomerular filtration rate; BIS, Berlin Initiative Study; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; cr, creatinine; cysc, cystatin C.
Simultaneously, the X-MAP technology was employed for the measurement of the four previously mentioned urinary markers: IP-10 (CXCL10), CysC, NGAL and KIM-1.
The isoelectric point of cysC is 9.3 which is why the protein is positively charged in the body fluids.
Serum cystatin C (CysC) has been proposed as a novel biomarker of the renal function [8].
Patients with overt DN who take orally a lecithinized formulation of rhein turned better through decreasing microglobulin blood beta 2 ([beta]2MG), serum creatinine (Scr), serum cystatin C (CysC), and urinary albumin excretion rate (UAER) [36].