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References in periodicals archive ?
Morfis et al., "Multiple amylin receptors arise from receptor activity-modifying protein interaction with the calcitonin receptor gene product," Molecular Pharmacology, vol.
Pharmacological discrimination of calcitonin receptor: receptor activity-modifying protein complexes.
To further identify the effects of PTL on osteoclastogenic differentiation in RAW264.7 cells, expression of osteoclast-related genes, including RANK, Calcitonin Receptor, Carbonic Anhydrase II, MMP-9, Cathepsin K, and TRAP, was investigated following coculture with treated hPDLCs (Figure 6).
In our coculture study, osteoclast differentiation related markers, including RANK [28] and Calcitonin Receptor [30], were reduced in RAW264.7 cells when they were cocultured with PTL-treated hPDLCs.
All osteoclastic markers including calcitonin receptor, TRAP, and cathepsin K were expressed, confirming the presence of osteoclasts or their late precursors in the periosteum.
Glucocorticoid and calcitonin receptor expression in central giant cell lesions: implications for therapy.
Calcr, a brain-specific imprinted mouse calcitonin receptor gene in the imprinted cluster of the proximal region of chromosome 6.
Calcitonin receptors are most prevalent in bone (osteoclasts), kidney (renal tubular cells), the central nervous system and the gastrointestinal tract, but are also expressed by macrophages and some breast and lung cancer cells.
The mRNA expression of the osteoclast-related markers, TRAP, cathepsin K, MMP-9, calcitonin receptor, carbonic II, and integrin 3[beta], decreased by meformin treatment.
Down regulation of Calcitonin receptor mRNA expression by Calcitonin during human osteoclast-like cell differentiation.
Induction of calcitonin receptors by 1[alpha], 25-dihydroxyvitamin [D.sub.3] in osteoclast-like multinucleated cells formed from mouse bone marrow cells.
Calcitonin is found in portions of the central nervous system (CNS) and pituitary gland, and investigators have speculated that it may act as a neurotransmitter or neuromodulator.[17-19] Studies in rodents have found high concentrations of calcitonin receptors in the periaqueductal gray matter and mesencephalic reticular formation.[20] Furthermore, salmon calcitonin was found to have significant analgesic effect when injected directly into the CNS.[20,21] The analgesia induced by calcitonin has been found to be both resistant to naloxone and reversible.
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