CIN 1

(redirected from Cervical Intraepithelial Neoplasia Grade 1)
AcronymDefinition
CIN 1Cervical Intraepithelial Neoplasia Grade 1
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The proposed Phase II/III trial is planned to be a randomised, double-blind, vehicle-controlled study of Topical Interferon Alpha-2b in patients with cervical intraepithelial neoplasia grade 1 or 2 lesions (CIN 1 or CIN 2 respectively).
Of the different strategies available for managing cervical intraepithelial neoplasia grade 1 (CIN1), testing for high-risk subtypes of the human papillomavirus (hr-HPV) DNA at 12 months has the highest sensitivity for predicting the development of CIN2 or CIN3 and leads to the lowest rate of referral to repeat colposcopy (TABLE 1).
Prospective follow-up suggests similar risk of subsequent cervical intraepithelial neoplasia grade 1 or negative colposcopy and directed biopsy.
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