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CRTZChemoreceptor Trigger Zone
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Commonly used antiemetic drug is prochlorperazine which is a phenothiazine derivative that limits stimulation of the chemoreceptor trigger zone. Antiemetics are definitely indicated in the management of this disease, Goddard and Leisewitz (2010).
The chemoreceptor trigger zone (CTZ) is a specialised region of the brainstem identified as the site for chemical stimulation of vomiting, and perhaps, nausea.
"Haloperidol is the most potent dopamine-2 antagonist at the chemoreceptor trigger zone. We don't think of it that way.