Medline (1966 to November 2013), EMBASE (1974 to November 2013), and Cochrane Controlled Trials Register
databases were searched to identify randomized controlled trials (RCTs) that referred to the impact of onabotulinumtoxinA in treating NDO; we also searched the reference lists of the retrieved studies.
The literature search identified more than 320 references of interest, mainly in PubMed and the Cochrane Controlled Trials Register
. LILACS (Latin American database), manual searches, Scirus, and ongoing registries did not provide any additional RCTs.
Metaanaiysis findings: The results of all the published studies on glucosamine and chondroitin (a disaccharide compound widely marketed in combination products with glucosamine) found in a MEDLINE search dating back to 1966 as well as in the Cochrane Controlled Trials Register
, identified 15 trials that were double blind, randomized, and placebo controlled (JAMA 283:146975, 2000).
The authors performed an adequate search of the literature, including not only Medline, but Embase, the Cochrane Controlled Trials Register
, and a hand search of meeting abstracts.
Two independent researchers performed an extensive search for both English-language and non-English-language studies on MEDLINE and the Cochrane Controlled Trials Register
, and in manuscript bibliographies and abstracts from scientific meetings.
The researchers searched 4 databases (PubMed, Embase, CINAHL, and Cochrane Controlled Trials Register
) and manually searched bibliographies from relevant articles, guidelines, and textbooks to find 2903 articles regarding diagnostic accuracy.
* STUDY DESIGN AND VALIDITY The reviewers searched the Register of Trials maintained by the Cochrane Pregnancy and Childbirth Group, the Cochrane Controlled Trials Register
, EMBASE, and the proceedings of the International and European Societies for the Study of Hypertension in Pregnancy.
The authors performed a MEDLINE search for studies pertaining to ACEIs, diabetes, and hypertension but did not search any other databases such as the Cochrane Controlled Trials Register
. Studies were included if they were randomized controlled trials of patients with type 2 diabetes that evaluated an ACEI versus another antihypertensive medication with a minimum follow-up of 2 years.
The studies were identified by searching MEDLINE (1966 to 1998), EMBASE (1988 to 1998), and the Cochrane Controlled Trials Register
(issue 3, 1998).