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[20] That colloid osmotic pressure does not play the role it was assigned by Ernest Starling is known to many burn surgeons, as burn oedema usually resolves in the face of dropping albumin levels.
During CPB operation, the exogenous liquid input was reduced, and the conditions maintained as follows: colloid osmotic pressure >12 mmHg, temperature 21-23[degrees]C, average blood pressure >40 mmHg, CPB flow 120-150 mL/kg.
In the present study, Hemospan was administered as an oxygen carrier with high molecular size, a colloid osmotic pressure of 70 mm Hg, and increased oxygen affinity.
The pressures involved in the Starling equation are (1) hydrostatic pressure in the pulmonary capillary, (2) colloid osmotic pressure in the pulmonary capillary, (3) hydrostatic pressure in the pulmonary interstitium, and (4) colloid osmotic pressure in the pulmonary interstitium.
In case of transudative pleural effusion, systemic factors govern the build-up of fluid including increased systemic and/or pulmonary capillary hydrostatic pressure (increased pulmonary capillary wedge pressure of 10cm H2O or more), decreased colloid osmotic pressure in the systemic circulation, or both (Light 2005).
Colloids are suspensions of particles of various sizes that aim to maintain plasma volume by maintaining the colloid osmotic pressure in plasma and thus retain the administered volume within the circulation.
This can be related to autonomic neuropathy (lack of vasoconstriction and increased cardiac output in response to decreased blood volume) and hypoalbuminaemia from gross proteinuria or poor nutrition (decreased fluid shifts between body fluid compartments because of the reduced colloid osmotic pressure, affecting vascular refilling rate).
These include hemodilution, cardiac cachexia, biventricular heart failure, reduced colloid osmotic pressure causing pulmonary edema, and reduced tolerability and use of optimal medical therapy, said Dr.