SMR decreased the most for patients with transposition of great arteries (early: 11 versus late: 3.8), complete atrioventricular canal
(31.3 versus 15.3), and single ventricle (53.7 versus 31.3).
Sadie was born with a complete atrioventricular canal
defect, a congenital condition characterized by a large hole in the wall between the heart's upper chambers, plus problems with the valves that regulate blood flow, according to the Mayo Clinic.
"Sadie was born with a complete atrioventricular canal
defect and underwent two open heart surgeries in her first few months of life," according to Seattle Children's Hospital, which offered the toddler's parents the chance to be in a Food and Drug Administration trial.
He also had a hole between the top chambers of his heart (complete atrioventricular canal
) and a hole between the bottom chambers.
The cardiac ultrasound scan confirmed an acyanotic cardiac lesion with a complete atrioventricular canal
defect, a common atrium, an interrupted inferior vena cava, a small patent ductus arteriosus and a moderate ventricular septal defect.
Down's syndrome, complete atrioventricular canal
, and pulmonary vascular obstructive disease.