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References in periodicals archive ?
"Robinson was diagnosed with Cortical Dysplasia, which occurs when the top layer of the brain does not form properly.
Connor McConnachie, who is six years old, was born with focal cortical dysplasia (FCD) and developed epilepsy because of this.
Ellie Rose Richardson, 10, suffers from the brain abnormality cortical dysplasia.
In the follow-up, cranial magnetic resonance imaging (MRI) was performed, which revealed an increase in the number of gyri, signal changes suggestive of polymicrogyria, and cortical dysplasia, calcification, leptomeningeal thickening, and asymmetric enlargement of the right lateral ventricle.
Our patient was a 32-year-old male, non-hypertensive, non-diabetic, who fulfilled five major criteria (facial angiofibromas, periungual fibromas, ash leaf spots, cortical dysplasia, subependymal nodules (SEN), renal angiomyolipomas) of tuberous sclerosis complex (TSC) as per diagnostic criteria of the 2012 International Tuberous Sclerosis Complex Consensus Conference (Box 1).4
HME may occur as an isolated disease or as a part of Proteus syndrome, neurofibromatosis, linear sebaceous nevus syndrome, tuberous sclerosis complex, or Klippel-Weber-Trenaunay syndrome.2 The typical characteristics of isolated hemimegalencephaly (iHME) include ipsilateral severe cortical dysplasia or dysgenesis, white matter hypertrophy and a dilated and dysmorphic lateral ventricle.3 This asymmetric and enlarged brain tissue is associated with intractable seizures, developmental delay, contralateral hemiparesis, and hemianopia.4 Because there is no cure for iHME, the principal aim of the treatment of this disease is to control seizures, which is done by using a variety of anti-epileptic drugs.4
Opercular abnormalities may be caused by genetic factors, as usually seen in Miller-Dieker syndrome,[sup][23] glutaric aciduria type 1,[sup][24],[25] methylmalonic acidaemia,[sup][26] and nonsyndromic microencephaly.[sup][27] However, abnormal operculization on prenatal imaging does not systematically reflect the underlying cortical dysplasia. It may be related to extracortical factors.[sup][28],[29] We should take ventriculomegaly, frontal hypoplasia, subarachnoid broadening arachnoid cyst, and other cerebral abnormalities into account.
Abnormalities of gyration, heterotopias, tuberous sclerosis, focal cortical dysplasia, microdysgenesis, dysembryoplastic neuroepithelial tumour and dysgenesis of the archicortex in epilepsy.
Hypopigmented lesions, cortical dysplasia, rabdomyomas, subependymal nodules were detected as major findings and renal cysts as minor findings and TS was diagnosed.
The main causes of epilepsy in children are cortical malformations (hemimegalencephaly, cortical dysplasia, lissencephaly, etc.) and phakomatoses (Tuberous sclerosis, Sturge-Weber disease, neurofibromatosis type 1, etc.), perinatal ischaemia, infections, mesial temporal sclerosis, metabolic diseases and tumours.
In 2014, he donated ( $83,000 to cover the medical costs of a 10-month-old boy suffering ( from cortical dysplasia , a rare neurological disorder.
After 17 years of her seizure onset, her thin section cranial MRI revealed right parietal cortical dysplasia. She still has seizures starting with left arm numbness and weakness, then tonic posture once a month under antiepileptic treatment.