Mice overproducing this protein, called Crry
, were about eight times as likely to survive at least 42 weeks as other lupus-prone mice were, the researchers found.
Royer et al., "Altered renal tubular expression of the complement inhibitor Crry
permits complement activation after ischemia/reperfusion," The Journal of Clinical Investigation, vol.
" Both Lesley and Allan" Both Lesley and Allan carry the faulty gene that crry
the faulty gene that causes hyperekplexia, but fortunately their eldest son, Josh, seven, did not inherit the illness.
Tumor-specific inhibition of membrane-bound complement regulatory protein Crry
with bispecific monoclonal antibodies prevents tumor outgrowth in a rat colorectal cancer lung metastases model.