Melatonin also diminished the half-life of mRNAs coding for both CuZnSOD
and GSH-Px, without altering that of MnSOD.
e uma enzima citosolica com atividade similar em diversos tipos de fibras musculares.
These investigations strongly suggest that overexpression of CuZnSOD and APX helped CA seeds to keep ROS under control by detoxifying superoxide radicals and H2O2, which paved the way for increased germination and seedling growth in various combinations of environmental stresses.
We hypothesized that overexpression of CuZnSOD and APX in transgenic tobacco plants may lead to improved tolerance against abiotic stresses during germination and seedling growth.
Expressions of CuZnSOD, MnSOD and Catalase gene were detected in control, melatonin and SNP plus melatonin groups, but these genes were not expressed in the SNP 1,000 |mM group.
Expressions of CuZnSOD, MnSOD and Catalase genes were detected in control, melatonin (1,000 [micro]M) and SNP (1,000 [micro]M) plus melatonin (1,000 [micro]M) groups, while these genes were not expressed in the SNP 1,000 [micro]M group.
Antioxidant enzymes (MnSOD, CuZnSOD
, Gpx, glutamylcysteine synthetase (GCS) and catalase) as an embryotropic factor were constituently expressed in both bovine oviduct cell monolayers and nonattached epithelial cell vesicle cultures during an 8-day culture period (Harvey et al.
Utilizing direct central injections of adenovirus encoding CuZnSOD
into the MnPO, we demonstrated an attenuated hypertensive response to chronic intravenously administered AngII .
has been correlated with a critical role in the protection of the blood vessels in response to oxidative stress during aging.
These findings suggest that imexon leads to an adaptive response to oxidative stress involving upregulation of several antioxidant genes such as Nrf2  and CuZnSOD
Collister and colleagues reported that selective overexpression of superoxide dismutase (SOD) in one of the circumventricular organs (organum vasculosum of the lamina terminalis, OVLT) via injection of adenoviral vectors encoding human CuZnSOD
(SOD1) significantly decreases blood pressure in an AngII-induced rat model of hypertension.
SOD is a very important antioxidant enzyme in mammals existing in three different physiological forms: MnSOD in the mitochondrial matrix, CuZnSOD
in the cytoplasm, and CuZnSOD
in extracellular fluids .