CTLA4

(redirected from Cytotoxic T-Lymphocyte Antigen 4)
AcronymDefinition
CTLA4Cytotoxic T-Lymphocyte Antigen 4
CTLA4Cytotoxic T-Lymphocyte-Associated Protein 4 (gene)
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References in periodicals archive ?
Yang et al., "Functional genetic variations in cytotoxic T-lymphocyte antigen 4 and susceptibility to multiple types of cancer," Cancer Research, vol.
Kolb-Maurer et al., "A polymorphism in the human cytotoxic T-lymphocyte antigen 4 (CTLA4) gene (exon 1 +49) alters T-cell activation," Immunogenetics, vol.
AMSTERDAM -- The highly promising new class of investigational anticancer agents known at cytotoxic T-lymphocyte antigen 4 blockers has a characteristic group of side effects, Dr.
Yoshizawa et al., "Association analysis of cytotoxic T-lymphocyte antigen 4 gene polymorphisms with primary biliary cirrhosis in Japanese patients," Journal of Hepatology, vol.
Larson et al., "Carriage of a tumor necrosis factor polymorphism amplifies the cytotoxic T-lymphocyte antigen 4 attributed risk of primary biliary cirrhosis: evidence for a gene-gene interaction," Hepatology, vol.
Pan et al., "Association between cytotoxic T-lymphocyte antigen 4 gene polymorphisms and primary biliary cirrhosis in Chinese population: data from a multicenter study," Journal of Gastroenterology and Hepatology, vol.
Yamamoto, "+49A/G polymorphism of cytotoxic T-lymphocyte antigen 4 gene in type 1 autoimmune hepatitis and primary biliary cirrhosis: a meta-analysis," Hepatology Research, vol.
Ipilimumab, approved in 2011 and marketed as Yervoy by BMS, is a human cytotoxic T-lymphocyte antigen 4 (CTLA-4)-blocking antibody indicated for treating unresectable or metastatic melanoma.
Abbreviations IL: Interleukin IFN[gamma]: Interferon gamma TNF[alpha]: Tumor necrosis factor alpha TLR: Toll like receptor CTLA-4: Cytotoxic T-lymphocyte antigen 4 DCs: Dendritic cells BMDCs: Bone marrow dendritic cells MAGE-AX: Melanoma-associated antigen AX GM-CSF: Granulocyte macrophage colony-stimulating factor MIF: Mean fluorescence intensity.
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