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D4RD4 Dopamine Receptor
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An analysis of the neuroimaging evidences used in diagnosis of this disorder, and the data obtained from the genetic linkage studies, provide a possible etiology in a deficit of the cerebral catecholaminergic system, specifically the D4 dopamine receptor and its transporter.
A version of the D4 dopamine receptor gene, or D4DR, cited as a key factor in producing novelty-seeking behavior (SN: 1/6/96, p.
One version of the so-called D4 dopamine receptor gene, or D4DR, appears frequently in people who report high levels of "novelty seeking," according to two independent studies reported in the January Nature Genetics.