DAMGOD-Ala2-MePhe4-Glyol5 Enkephalin (synthetic opioid peptide)
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3]H]diphrenorphin and the competitive ligand are mitragynine, naltriben, U-69593 and DAMGO with increasing concentration.
The affinity of [mu]-opioid-receptor agonists such as morphine; diprenorphine; n-Ala(2),N-MePhe(4),Gly(5)-olenkephalin (DAMGO); [beta]-endorphin; metenkephalin; and dynorphine was not changed, but the potency and efficacy of DAMGO, (3-endorphin, and morphine were decreased (22).
Trizma hydrochloride, dimethyl sulfoxide, (D-Ala2, N-Me-Phe4, glisinol5)-encephalin or DAMGO and (5,7,8(3)- N- methyl- N - [7-(1-pyrolidinyl)1-oxaspyro [4,5] dek- 8- il] benzenacetamide or U69,593 (Sigma St.