DDAH

AcronymDefinition
DDAHDimethylarginine Dimethylaminohydrolase
DDAHDesordem por Défice de Atenção com Hiperactividade (Portuguese: Attention Deficit Disorder with Hyperactivity)
References in periodicals archive ?
However, the increased production of NO by iNOS, primed by inflammatory cytokines, leads to an S-nitrosylation of reactive cysteine in DDAH, inhibiting ADMA catabolism, thus increasing its levels and lastly inhibiting all three isoforms of NOS [26].
Asymmetric Dimethyl Arginine as a Biomarker of Atherosclerosis in Rheumatoid Arthritis
Hyperglycemia in type 2 diabetic patients impairs an enzyme, DDAH which is responsible for the degradation of ADMA, thus leading to high concentration of ADMA in blood8.
ENDOTHELIAL DYSFUNCTION AND DERANGED LEVEL OF ASYMMETRIC DIMETHYL ARGININE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS
In humans, DDAH exists as two isoforms, DDAH1 and DDAH2.
Modulating DDAH/NOS pathway to discover vasoprotective insulin sensitizers
DDAH activity in diabetic neuropathy patients should be examined in further clinical studies.
Serum asymmetric dimethylarginine and nitric oxide levels in patients with diabetic neuropathy/Diyabetik noropatili hastalarda serum asimetrik dimetilarginin ve nitrik oksit duzeyleri
Homocysteine induced accumulation of asymmetric dimethylarginine: role of DDAH and effect of antioxidants.
Effect of nebivolol and metoprolol treatments on serum asymmetric dimethylarginine levels in hypertensive patients with type 2 diabetes mellitus / Tip 2 diyabetes mellituslu hipertansif hastalarda nebivolol ve metoprolol tedavilerinin serum asimetrik dimetilarginin duzeyleri uzerine etkisi
Revisando la literatura sobre la relacion de los polimorfismos del gen VEGF, aparte de los trabajos que si hallan asociacion -como los senalados anteriormente, y que incluyen aquellos sobre el polimorfismo del alelo +936, como los Shim (15) y Papazoglou (11)-, en otros mas recientes no se ha encontrado dicha asociacion con los polimorfismos de VEGF +936C/T (18), en el alelo +813C (20), los alelos menores VEGF rs699947, rs1570360, rs2010963 y rs25648 (21), polimorfismos de los genes eNOS, DDAH y VEGF (22), y con los polimorfismos del gen de VEGF -2578C/A, -634G/C; el 936C/T en estudio, solo fue encontrado asociado con la preeclampsia severa (11).
Polimorfismo en el gen del factor de crecimiento vascular endotelial (VEGF) y su asociacion con la preeclampsia
ADMA is primarily metabolized to citrulline and dimethylamine by the enzyme dimethylaminohydrolase (DDAH), which has high activity in the liver and kidneys [69-71].
Reactive metabolites and AGE-RAGE-mediated inflammation in patients following liver transplantation
EFFECTS OF TOBACCO SMOKE ON ADMA LIBERATION AND DDAH EXPRESSION IN EAhy 926 CELLS
Asymmetric dimethylarginine, smoking, and risk of coronary heart disease in apparently healthy men: prospective analysis from the population-based Monitoring of Trends and Determinants in Cardiovascular Disease/Kooperative Gesundheitsforschung in der Region Augsburg study and experimental data
ADMA, the endogenous NO inhibitor, also increases in dyslipidemia probably due to inhibition of dimethyl diamino hydrolase (DDAH) which is the enzyme responsible for ADMA catabolism because of low grade chronic inflammation.
Nitric oxide and cardiovascular system/Nitrik oksit ve kardiyovaskuler sistem
Unchanged ADMA is excreted by the kidneys, but the greatest part of endogenously produced ADMA (about 90%) is excreted in the urine as dimethylamine (DMA) after hydrolysis by the enzyme dimethylarginine dimethylaminohydrolase (DDAH) [15], predominantly in kidney and liver.
L-Arginine/NO pathway is altered in children with haemolytic-uraemic syndrome (HUS)
Wild type (WT) C57BL/6 and dimethylarginine dimethylaminohydrolase transgenic (DDAH-I) mice on the C57BL/6 strain that overexpress DDAH were originally obtained from The Jackson Laboratory (Bar Harbor, ME) and subsequently bred and maintained in microisolator units in the UNMC specific pathogen-free animal facility.
Asymmetric dimethylarginine blocks nitric oxide-mediated alcohol-stimulated cilia beating
Dimethylamine dimethylaminohydrolase (DDAH) converts ADMA to citrulline and dimethylamine.
Should we measure asymmetric dimethylarginine in patients with coronary artery disease?
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