METHODS/RESULTS: Using permanent and primary human bronchial epithelial (HBE) cells at air-liquid interface, we show that DEPs
activate the human MMP-1 gene via RAS and subsequent activation of RAF-MEK-ERK1/2 mitogen-activated protein kinase signaling, which can be scaffolded by [beta]-arrestins.
vs George Lynham, S.C.: C.P., Deps
., 23 February 1864, SRNSW 9/6467, 6147/39.
QUEENSLAND: Austravel (0800 988 4834) offers nine-day twin-centre holiday on selected March deps
in Queensland from PS1,395, incl return Qantas flights ex-Heathrow, five nights' accom on Gold Coast at Vibe Hotel, internal flight and transfers and three nights' accom in Cairns at Cairns Colonial Club, saving PS180 per couple.
JOHANNESBURG Netflights (0844 493 4944) return Turkish Airlines flights ex-Gatwick from PS512, for deps
until Dec 9.
MALDIVES: Fourteen nights for pounds 629 dep
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NEW YORK: BA Holidays (0844 493 0758) offers three nights' room-only at three-star Jolly Madisson, from pounds 529, ex-Heathrow on deps
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The Environment Agency and the Construction Ministry plan to work out comprehensive measures to slash DEPs
, suspected carcinogen, in areas along Route 23 in Nagoya and its vicinities.
Diesel exhaust particles (DEPs
) are common airborne particulate matter that have diameters of < 2.5 [micro]m and contain adsorbed organic compounds, many of which are known to alter the pulmonary microsomal enzyme pool, which results in altered xenobiotic metabolism.
research has suggested that people who live in areas with high densities of airborne particulate matter, much of which is DEPs
, have a greater chance of dying from heart disease.
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