METHODS/RESULTS: Using permanent and primary human bronchial epithelial (HBE) cells at air-liquid interface, we show that DEPs
activate the human MMP-1 gene via RAS and subsequent activation of RAF-MEK-ERK1/2 mitogen-activated protein kinase signaling, which can be scaffolded by [beta]-arrestins.
vs George Lynham, S.C.: C.P., Deps
., 23 February 1864, SRNSW 9/6467, 6147/39.
It ensures that funding will be available to clean up hundreds of mine sites across West Virginia, said DEP
Cabinet Secretary Randy C.
QUEENSLAND: Austravel (0800 988 4834) offers nine-day twin-centre holiday on selected March deps
in Queensland from PS1,395, incl return Qantas flights ex-Heathrow, five nights' accom on Gold Coast at Vibe Hotel, internal flight and transfers and three nights' accom in Cairns at Cairns Colonial Club, saving PS180 per couple.
JOHANNESBURG Netflights (0844 493 4944) return Turkish Airlines flights ex-Gatwick from PS512, for deps
until Dec 9.
MALDIVES: Fourteen nights for pounds 629 dep
Gatwick, Dec 8, with Hayes & Jarvis.
NEW YORK: BA Holidays (0844 493 0758) offers three nights' room-only at three-star Jolly Madisson, from pounds 529, ex-Heathrow on deps
to March 31.
The Environment Agency and the Construction Ministry plan to work out comprehensive measures to slash DEPs
, suspected carcinogen, in areas along Route 23 in Nagoya and its vicinities.
Diesel exhaust particles (DEPs
) are common airborne particulate matter that have diameters of < 2.5 [micro]m and contain adsorbed organic compounds, many of which are known to alter the pulmonary microsomal enzyme pool, which results in altered xenobiotic metabolism.
research has suggested that people who live in areas with high densities of airborne particulate matter, much of which is DEPs
, have a greater chance of dying from heart disease.
Applicants are encouraged to undertake projects that address DEPs
priority topics of climate change, water education and environmental justice.
VALENTINE'S IN DURHAM Radisson Blu Hotel, Durham City (0191 372 7200) two nights' B&B from PS132, incl a three-course dinner at Filini Italian restaurant BRUSSELS Cresta (0844 879 8014) three nights' B&B at 3* Ibis Brussels off Grand Place from PS175, ex-St Pancras Apr 8, and incl upgrade to Standard Premier on Eurostar MIAMI Travel City Direct (0844 557 6965) four nights' room-only accom at Newport Beachside Hotel & Resort from PS839, ex-Heathrow, inc car hire, for deps
Mar 18-20 MEXICO First Choice (0871 200 7799) 14 nights' all-inclusive at 4* Grand Bahia Principe Akumal Resort from PS1,449, ex-Manchester Feb 27 and transfers RED SEA Holiday Designers (020 3384 0023) seven nights' half-board at 5* Hyatt Regency, Taba Heights, from PS545, ex-Manchester Feb 19 and transfers.