Carson is a key link in supplying multiple jet fuel supply chains emanating from the Los Angeles basin and any prolonged outage would result in mission failures for military and government customers throughout the West Coast,' said DLA Energy Americas at San Pedro Deputy Director Tracy Keenan.
The immunohistochemical finding of diffuse positivity of tumour cells with CD34+ helped in arriving at the final conclusive diagnosis of Dermatofibrosarcomaprotuberans (DFSP
Biopsy from the nodule raised the suspicion of DFSP
rather than breast cancer.
There were 124 (61.4%) cases of BCC, 33 (16.3%) cases of SCC, 14 (6.8%) cases of MF, 12 (5.8%) cases of DFSP
, 7 (3.7%) cases of MM, 3 (1.5%) cases of Bowen's disease, 3 (1.5%) cases of metastatic carcinoma, 3 (1.5%) cases of adnexal carcinoma, 1 (0.5%) case of pleomorphic dermal sarcoma (PDS), 1 (0.5%) case of Kaposi's sarcoma and 1 (0.5%) case of Merkel cell carcinoma (MCC).
BT is a rare variant of DFSP
, which is a locally aggressive spindle-cell mesenchymal tumour.
In our cohort, the most frequent skin malignancies were sclerodermiform BCC and DFSP
, which are frequently associated with wide excisions due to the risk of local recurrence .
Dermatofibrosarcoma protuberans (DFSP
) is a locally aggressive soft tissue neoplasm with intermediate malignant potential, regarded as a low grade sarcoma by the WHO classification of tumours of the skin.
The final histological diagnosis was DFSP
. The patient was then referred to our Breast Unit at the Royal Hospital and the case was reviewed by a multidisciplinary team including surgeons, pathologists, oncologists, and radiation oncologists.
A chest computed tomography scan is routinely used to look for metastases, but it is not appropriate in sarcomas that rarely metastasise, such as dermatofibrosarcoma protuberans (DFSP
Grading was deemed as "not applicable" (1) in certain sarcomas considered routinely to display aggressive or "high grade" behaviour, (2) in metastatic tumours, (3) in tumours not formally graded, such as dermatofibrosarcoma protuberans (DFSP
), (4) in benign lesions, (5) if there was a difference in diagnosis between the referring and specialist unit report, making grading noncomparable, or (6) if there was insufficient material for grading.
CD34 positivity in Spindle cell tumour more favoring diagnosis of Dermatofibrosarcoma protuberans which is helpful in diagnosing DFSP
and distinguishing it from other tumours like dermatofibroma, benign fibrous histiocytoma etc.
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