DHGLADihomo-Gamma-Linolenic Acid (NIDDM predictor, medicine)
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has been identified as a source of PUFAs mainly arachidonic acid (AA) at an average value of 30-70% and other PUFAs such as linoleic acid (LA), gamma-linolenic acid (GLA), and dihomo-gamma-linolenic acid (DHGLA) at significant levels [3].
It was also noticed that culture medium supplemented with general vegetable oils gave the low yield ofbiomass, lipid, and individual PUFA levels when compared to ALA-rich oils such as GCO, CO, and LSO, when LSO supplement in the growth medium could be able to convert the DHGLA into EPA by the action of [[DELTA].sup.5,6] desaturase enzymes and similarly LSO supplementation resulted in the highest yield of DHA followed by CO and GCO supplementations.
The conversion of [omega]-6 fatty acids such as GLA, DHGLA, and AA to [omega]-3 fatty acid, especially the EPA and DHA, was possible by the change in the pathway utilizing elongase as well as [[DELTA].sup.6,5,17] desaturase enzymes.