The patient developed a progressive distal numbness and limb weakness 5 days after DMAB
intoxication, and neurologic examinations showed generalized hyporeflexia; decreased sensation in pin-prick, temperature, touch, vibration, and position sensations; and weakness in the distal limbs, particularly in both feet (Kuo et al.
CASE PRESENTATION: Three patients exposed to DMAB decontaminated immediately by drinking a lot of water; they reported dizziness, nausea, diarrhea 6-8 hr later.
DISCUSSION: This case study demonstrates that DMAB is highly toxic to humans through any route of exposure, and dermal absorption is the major route of neurotoxicity.
RELEVANCE: Further investigation of the toxic mechanism of DMAB is warranted.
DMAB is a white, crystalline solid with a molecular weight of 58.
Here we report a case of occupational DMAB exposure that caused significant neurotoxicity.
A 36-year-old, healthy male was accidentally sprayed over the face and trunk with the liquid form of DMAB (Figure 2).
DMAB was the only toxic substance at the workplace.
There were three other workers with a history of DMAB contamination.
To our knowledge, the human toxicity of DMAB has never been reported in the literature.