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DMDDuchenne Muscular Dystrophy
DMDDoctor of Dental Medicine
DMDDigital Micromirror Device (Texas Instruments)
DMDDisability Mentoring Day
DMDDisaster Management Department (various organizations)
DMDDante Must Die
DMDDeputy Medical Director (various organizations)
DMDDirect Metal Deposition (manufacturing technology)
DMDDystrophie Musculaire de Duchenne (French: Duchenne Muscular Dystrophy)
DMDDigital Micromirror Device
DMDDifferential Mode Delay
DMDDigital Music Download
DMDData and Music Drive
DMDDigital Multilayer Disk
DMDDélégation Militaire Départementale (French: Military Departmental Delegation)
DMDDielectric Metal Dielectric (heat reflector)
DMDDiscrete Molecular Dynamics (chemical physics)
DMDDirectory Management Domain
DMDDrug Metabolism and Disposition
DMDDisease Modifying Drug
DMDDigital Mirror Device
DMDDifferential Mode Delay (multimode optical fiber)
DMDDevelopment Management Document (UK)
DMDDeputy Managing Director (International Monetary Fund)
DMDDigital Media Division (various organizations)
DMDDelta Mu Delta (Honor Society in Business Administration)
DMDDot Matrix Display
DMDDesmethyldiazepam (drug)
DMDDoctor of Medical Dentistry
DMDDeformable Mirror Device
DMDDidier Morain Distribution (French pet supply company)
DMDDance My Dunce
DMDDystonia Musculorum Deformans
DMDDigital Mars D Compiler
DMDDiet Mountain Dew (PepsiCo)
DMDData Monitor and Display
DMDData Management Division
DMDDiscontinuous Molecular Dynamics
DMDDiscover Mongolia & Development (travel agency)
DMDDigital Music Distributor
DMDDistance Measuring Device
DMDDifferential Metabolic Display
DMDDigital Multilayer Disc
DMDDigital Message Device
DMDDynamic Mobile Data
DMDDoctorants en Mathématiques à Dijon (French: Doctoral Students in Mathematics in Dijon; Dijon, France)
DMDDelta Marketing Dynamics
DMDDomestic Manufacturing Deduction (US Taxes)
DMDDifferential Modulation Diversity
DMDDomain Management Device
DMDDepartment of Mission and Development
DMDDance Monkey, Dance (Internet slang)
DMDDental/Medical Diagnostic Systems, Inc. (former stock symbol; now delisted)
DMDData Mapping Document
DMDDelivery Mode Detail (Canada Post)
DMDDentariae Medicinae Doctoris (Doctor of Dental Medicine)
DMDDual Mode Display
DMDDeployment Manning Document
DMDData Message Device
DMDDigital Map Display
DMDDubai Municipality Datum
DMDData Measurement Device
DMDDuty Mission Director
DMDDowntown Management Districts
DMDDevices Management Directorate
DMDDual Multiplexer Demultiplexer
DMDDispersion Management Devices (Lasercomm)
DMDDivision of Medical Device (National Institute of Health Sciences; Japan)
DMDDiphenyl-Methane Diisocyanate
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References in periodicals archive ?
There are many types of intraocular surgeries such as phacoemulsification, trabeculectomy, deep sclerotomy, viscocanalostomy, holmium laser sclerostomy, deep anterior lamellar keratoplasty, endothelial keratoplasty, intracorneal ring segment implantation, and pars plana vitrectomy, that are known to result in DMD. (10-18) Among the most common causes of DMD are blunt keratomes, shelved or anteriorly placed incisions, shallow anterior chamber, inadvertent injection of saline, viscoelastic or antibiotics at the pre-Descemetic space such as during irrigation-aspiration, stromal hydration, intraocular lens insertion, and intracameral antibiotic injection.
There is currently no cure for and most DMD patients die by the age of 16.
"This is the first time that we have seen positive gene therapy results in large mammals of DMD," Duan said.
TNF-[alpha] is upregulated in DMD sera [14] with levels increased 1000 times in comparison to levels in healthy subjects [15].
Duchenne muscular dystrophy is caused by deletion, duplication or point mutation of the DMD gene1 located on short arm of X chromosome (Xp21), which encodes dystrophin2.
The clinical development program with vamorolone in patients with DMD was initiated following a clinical pharmacology study (VBP15-001) in healthy volunteers in which biomarker assessments indicated reduced occurrence of side effects typical for traditional corticosteroid drugs, such as prednisone and deflazacort (bone fragility, metabolic disturbance, immune suppression) [2].
The effects of edasalonexent on bone health are being further studied in DMD in the ongoing global Phase 3 PolarisDMD trial, which includes dual-energy X-ray absorptiometry to assess bone density and body composition and standardized lumbosacral spine films to assess for fractures at baseline and following one year of treatment.
- The largest proportion of industry-sponsored drugs in active clinical development for DMD are in Phase II.
When he was a child Ian, says information about DMD was hard to come by.
Vertex and CRISPR Therapeutics (NASDAQ: CRSP) have expanded their collaboration and entered into an exclusive licensing agreement to discover and develop gene editing therapies for the treatment of DMD and DM1.
"Children with DMD often die either because their heart loses the strength to pump, or their diaphragm becomes too weak to breathe," said Dr Eric Olson, Director of UT Southwestern's Hamon Center for Regenerative Science and Medicine in Dallas, US.