Chou, "iDNA-prot: identification of DNA binding proteins
using random forest with grey model," PLoS ONE, vol.
coli-single-stranded DNA binding protein
(SSB) with exonuclease I.
FBP1 is a single stranded DNA binding protein
that induces expression of MYC by binding to the FUSE site on the MYC promoter.
The AATT pattern which is found more frequently in NM matched with 151 DNA binding protein
consensus sequences, although very few are found in mammals.
The bacteriophage phi29 requires only four proteins (including polymerase, terminal protein, single-stranded and double-stranded DNA binding proteins
) and two DNA elements (origin of replication and high affinity sites for its double-stranded DNA binding protein
) to replicate and maintain its linear genome, making it a suitable starting point for the development of an HNA episome.
Mutations in two RNA binding proteins involved in RNA splicing, the Tar DNA binding protein
of 43kd (TDP-43) and Fused in Sarcoma (FUS), cause amyloid aggregation and are associated with Amyotrophic Lateral Sclerosis (ALS).
iDBPs: a web ser\'er for the identification of DNA binding proteins
. Bioinformatics 2010;26(5):692-693.
Representative subjects of research presented this year included: gene suppression in Aspergillus nidulans, physical properties of the amphipathic protein hydrophobin, heavy metals in hyperthermophilic archaea, heatshock response in wound healing, regulation of the cell signaling protein Janus kinase, and DNA binding proteins
in chloroplast nucleoids.
Development of Novel DNA Binding Proteins
as Antiviral Therapeutics (Sangamo BioSciences, Inc., Aurora, CO).
He has authored over 60 publications relating to the development of customized DNA binding proteins
and nucleases for genome editing.
Two DNA replication relate proteins that may heavily rely on differences in duplex stability in replication relevant architectures are the single-stranded DNA binding proteins
(SSBs) and DNA polymerases.
Using an in vivo assay called Chromatin Immunoprecipitation (CHIP), DNA binding proteins
are reversibly cross-linked to chromatin in cells.