The purpose of the study was to explore the influence of a 6-minute walk test (6MWT) as a simple, non-invasive tool to detect RV dysfunction in patients with DPLD.
13) The analysis was limited to the patients with DPLD.
The patients who had RV dysfunction also had lower percentage predicted DLCO irrespective of the clinical characteristics (including demographics, WHO functional class, and the severity of DPLD based on lung function, i.
15,23) Additionally, 6MWD has an advantage as a prognostic value in patients with DPLD.
Nonetheless, early PH identification in DPLD may permit more aggressive management of the underlying lung disease and identify patients needing lung transplant evaluation.
Up to 10% patients of biopsy proven DPLD have normal chest X-Ray.
HRCT is often in itself diagnostic, and should always precede biopsy in the investigation of DPLD.
TBLB achieves a high diagnostic yield in DPLDs with centrilobular attenuation, such as granulomatous and metastatic diseases, infection, alveolar proteinosis and eosinophilic pneumonias.