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DQ2Dragon Quest II (gaming)
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Only after obtaining presence of HLA DQ2.2 haplotype, the gastroscopy was repeated with the biopsy of duodenum, which made the diagnosis possible.
Tissue Transglutaminase (TTG) TTG IgA no Celiac disease TTG IgG no Celiac disease Deamidated Gliadin Peptide (DGP) DGP IgA no Celiac disease DGP IgG no Celiac disease Anti-gliadin Antibody (AGA) AGA IgA no Celiac disease AGA IgG no Celiac disease/NCGS Endomysial Antibody IgA no Celiac disease Wheat specific IgE no Wheat llerqy (IqE) HLA DQ2 and DQ8 yes Celiac disease/NCGS Lab Test Sensitivity Specificity Tissue Transglutaminase (TTG) TTG IgA 98% 98% TTG IgG 70% 95% Deamidated Gliadin Peptide (DGP) DGP IgA 88% 95% DGP IgG 80% 98% Anti-gliadin Antibody (AGA) AGA IgA 85% 90% AGA IgG 85% (CD) 80% (CD) Endomysial Antibody IgA 95% 99% Wheat specific IgE 83% 43% HLA DQ2 and DQ8 rv100% low; varies (CD) depending on population
Type 1 EATL is associated with celiac disease, and has HLA DQ2 and HLA DQ8 genotype (7).
We have reported a significantly high frequency of the HLA class II antigens DR4, DR7, and DQ2 in Turkish patients with MTLE--HS (11).
Specifically, DQ2S broken lance would be in this instance a sexist metaphor for impotence, both in reality and in fantasy, because DQ2S phallic lance is broken and DQ3 is slaying a feminized, prancing block figure.
Symptomatic patients with serologic levels of immunoglobulin A anti-tissue transglutaminase (IgA anti-tTG) or immunoglobulin G anti-deamidated gliadin peptide antibody (IgG anti-DGP) greater than 10 times the upper limits of normal--especially if they also are positive for endomysial antibodies (EMA) and human leukocyte antigen DQ2 (HLA-DQ2 or HLA-DQ8)--may not need an intestinal biopsy to confirm the diagnosis of celiac disease (strength of recommendation [SOR]: B, inconsistent or limited-quality cohort studies).
(19) Existe uma forte influencia genetica que predispoe a DC, envolvendo genes HLA (DQ2 e DQ8) e nao-HLA.
Both are associated with major histocompatibility complex class II antigen DQ2 encoded by alleles DQA1*501 and DQB1*201, thus providing a common genetic basis for the disease expression.
Since HLA-A1, A11, B8, B35, DR3, DR1, DQ2, DQ1 antigens have been described in the literature in association with rapid progression to AIDS (4,26) in many ethnic groups, these markers were considered for analysis in the present study.