An open-label cluster-randomized controlled trial was designed for comparing SRDTs for HIV and syphilis with DRDTs for HIV and syphilis.
Clusters were randomly allocated to Arm A (SRDTs) or to Arm B (DRDTs) with a 1:1 allocation ratio, using SAS software (19).
Tests were performed according to the manufacturer's guidelines, using blood collected by a finger stick, one drop per cartridge for the SRDTs and one drop for the DRDTs.
There were no reports of serious adverse events in patients or health workers related to the use of SRDTs or DRDTs during the study.
Our data also shows differences between SRDTs and DRDTs in terms of timely treatments when the effect was adjusted by region and period.
There are limited data that compare both SRDTs and DRDTs in terms of acceptability, testing, and timely treatment in the first 24 hours.
This study has the limitation of not having used gold standard tests for HIV and syphilis as a means of comparison of the SRDTs and DRDTs used; thus, it was not possible to establish the accuracy of the tests.