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GCR-3888 is an immunotoxin fusion protein between a murine anti-CD22 disulphide-linked Fv antibody fragment (dsFv) and the Pseudomonas exotoxin PE38, and GCR-8015 is an optimized version of GCR-3888 with increased affinity for CD22.
Kay Kuczynski, DSFV, LCSW, maintains a small private practice and is assistant professor, and Patty Gibbs-Wahlberg is program director and professor, Department of Social Work, East Tennessee State University, PO Box 70645, Johnson City, TN 3 7614-0002.
At ASCO, NeoPharm also unveiled new preliminary Phase I data from NeoPharm's Tumor-Targeting Platform on two novel compounds: IL13-PE38 and SS1(dsFv)-PE38, both for the treatment of advanced malignancies.