TGF-[beta] is a multifunctional cytokine involved in cell growth, proliferation, and differentiation, as well as in extracellular matrix synthesis, indicating an important role for the signaling pathways involved in odontogenic differentiation; this includes the upregulation of the expression of noncollagenous proteins such as DSPP
and DMP-1 , as supported by our results.
(a) In SCAP-Foxc2-BMP2, the mRNA expression of ALP, OCN, DSPP
, and DMP1 was significantly higher than that of the other groups at majority of the time points (P < 0.05).
The expressions of DSPP
, ALP, OCN, BMP-2 and FGF2 mRNA in the ginsenoside Rg1 group (5 [mu]mol/l) showed a time-dependent increase compared with the control group (pLess than0.05), which remained little change in the period (Fig.
That cut Securities & Exchange Commission approval time of a company-sponsored DSPP
to three or four months.
For example, companies such as AT&T (NYSE:T) and Wendy's International (NYSE: WEN), just to name two, offer DSPPs
and DRIPs to investors.
Moreover, the gene expression levels of the related odontogenic gene markers such as DSPP
, DMP-1, Runx2, and OCN were measured to elucidate the effects of the CPC + CN + 50Met composite on the odontogenic differentiation in vitro.
, one of the dentin markers, was strongly detected in hDPSCs lined on the surface of DDM (Figure 7(e)) than those on the surface of HA-TCP transplanted.
The company added that the units may be purchased under the DSPP
at any time prior to 17:00 Eastern Standard Time on 29 November 2013.
reported enhanced ITGA1 expression leads to the differentiation of human skeletal muscle stem cells (hSMSCs) into odontoblasts evidenced by upregulation of dentin sialophosphoprotein (DSPP
), dentin sialoprotein (DSP), and alkaline phosphatase (ALP) .
SIBLING family consists of noncollagenous proteins (NCPs), primarily involved in bone metabolism and mainly located within the mineralized tissue such as bone and dentin, which also includes bone sialoprotein (BSP (IBSP)), dentin matrix protein 1 (DMP1), dentin sialophosphoprotein (DSPP
), and matrix extracellular phosphoglycoprotein (MEPE) [5, 6].
After osteogenic differentiation for 7 days and 14 days, the expressions of important osteogenesis-related genes, including alkaline phosphatase (ALP), bone sialoprotein (BSP), dentin sialophosphoprotein (DSPP
), and osteocalcin (OCN), were detected by RT-PCR as previously described .