According to the tests, this system significantly decreases the side effects of daunorubicin
drug in the control cells, and it increases its therapeutic effects in the target cells in comparison with the drug without carriers.
No patient died during the vincristine, daunorubicin
, L-asparaginase and dexamethasone (VDLD) induction treatment, and only one patient with appendicitis required treatment in an intensive care unit.
The compounds like Neothramycin, Daunorubicin
and Aclarubicin showed slightly better interaction with the mutation of glutamate with Glu at residual position 292.
A randomized investigation of high-dose versus standard-dose cytosine arabinoside with daunorubicin
in patients with previously untreated acute myeloid leukemia: a Southwest oncology group study.
One mechanism by which this opposition, commonly known as chemoresistance, happens is through the expression of drug transporter pumps in leukemia cells that actively pump out chemotherapeutics, including Daunorubicin
11) revealed that anti-leukemia drugs such as Ara-C and daunorubicin
promote DR5 expression in leukemic cell lines and induce a cytotoxic effect.
2] was started and daunorubicin
was added on the 3rd day after starting ATRA.
Generic cancer drugs that are in short supply include fluorouracil (5-FU), pa-clitaxel, daunorubicin
, cytarabine, bleomycin, and cisplatin.
The sensitivity of Mtx and daunorubicin
(Dnr) combination was highly significant in responder group (p = 0.
Chemotherapy was employed for the remission of the leukaemia, consisting of the administration of prednisone, vincristine, daunorubicin
, L-asparaginase and methotrexate/ara-C/dexamethasone IT.
33) List Assigned number Arsenic trioxide (Trisenox[R]) P P012 Cyclophosphamide (Cytoxan[R]) U U058 Chlorambucil (Leukeran[R]) U U 035 Daunorubicin
(Daunomycin[R], Cerubidine[R]) U U059 Diethylstilbestrol U U089 Melphalan (Alkeran[R]) U U150 Mitomycin (Mitomycin C[R], Mutamycin[R]) U U010 Streptozocin (Zanosar[R], Streptozocin[R]) U U206 Uracil Mustard (Uramustine[R]) U U237 * U.
Using a mouse model of obesity and leukemia, researchers cultured fat and leukemia cells together and treated the leukemia cells with traditional chemotherapy drugs: vincristine, nilotinib, daunorubicin
, and dexamethasone.