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TDTHDelayed-Type Hypersensitivity (T-cell)
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A study revealed that granuloma annulare might be caused by a delayed-type hypersensitivity reaction.
A specific prebiotic oligosaccharide mixture stimulates delayed-type hypersensitivity in a murine influenza vaccination model.
In particular, delayed-type hypersensitivity, accumulations of immune complexes, and cytokine-mediated changes are considered in its etiology, and its effect on vascular hemostasis is mentioned (1).
To monitor the delayed-type hypersensitivity reaction dinitrochlorobenzene (DNCB) test was used as explained by Blumink et al.
but they also provoke late and delayed-type hypersensitivity much more often--and more severely --than do pollens.
(2000) Mast cells control neutrophil recruitment during T cellmediated delayed-type hypersensitivity reactions through tumor necrosis factor and macrophage inflammatory protein 2.
In TST, the measurement of delayed-type hypersensitivity (DTH) reaction due to inflammatory reaction after the in vivo intradermal injection of tuberculin purified protein derivatives (PPD) (2).
MIF was originally reported in 1966 by two different groups and was described as a T cell derived cytokine that inhibited the random migration of macrophages in vitro and promoted macrophage accumulation during delayed-type hypersensitivity reactions [1, 2].
Abbreviations ConA: Concanavalin A LPS: Lipopolysaccharide DNFB: 2,4-Dinitrofluorobenzene DTH: Delayed-type hypersensitivity RA: Rheumatoid arthritis TCM: Traditional Chinese medicine TAPOs: A-type procyanidin oligomers PB-2: Procyanidin B2 CTB-1: Cinnamtannin B1 CTD-1: Cinnamtannin D1 PA-1: Parameritannin A1 PC-1: Procyanidin C1.
Th1 cells drive the type-1 pathway ("cellular immunity") to fight viruses and other intracellular pathogens, eliminate cancerous cells, and stimulate delayed-type hypersensitivity (DTH) skin reactions.
Three Protein Cocktail Mediate Delayed-Type Hypersensitivity Response Indistinguishable from that Elicited by Purified Protein Derivative in the Guinea Pig Model of Mycobacterium tuberculosis Infection.
The depressed delayed-type hypersensitivity reaction may also explain the negative result of tuberculin skin test seen in our patient.