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References in periodicals archive ?
They, however, failed to comply with the specification for assay of dihydroartemisinin.
The piperaquine reference substance was unavailable; therefore, dihydroartemisinin/piperaquine samples were evaluated based on the quality and quantity of only the dihydroartemisinin component.
Basilico, "Stability of the antimalarial drug dihydroartemisinin under physiologically relevant conditions: Implications for clinical treatment and pharmacokinetic and in vitro assays," Antimicrobial Agents and Chemotherapy, vol.
Antimalarial drug containing the combination of dihydroartemisinin (80mg) and piperaquine phosphate (640mg) per 80ml was purchased from a local pharmaceutical store in Nigeria.
Artemisinin and its derivatives, artesunate, artemether, and dihydroartemisinin, are the most rapidly acting of all antimalarials and have the fastest parasite clearance time, rapid resolution of symptoms, and an excellent safety profile.
(38) Nevertheless, therapy with piperaquine and dihydroartemisinin (DHA) has exhibited high effectiveness, safety, and tolerability.
falciparum (NF54), cryptolepine exhibited promising synergistic interactions in vitro with artesunate, artemether, dihydroartemisinin, and amodiaquine.
As per reported observations, optimum size (224.8-266.3 nm) was achieved for Clozapine loaded SLN with different lipids including tripalmitin and 1% poloxamer concentration [48] and 241 nm for dihydroartemisinin loaded solid lipid nanoparticles when formulated by single-emulsion solvent evaporation technique [30].
Dihydroartemisinin targets VEGFR2 via the NF-KB pathway in endothelial cells to inhibit angiogenesis.
The effect of co-administration of dihydroartemisinin with vitamin E on the activities of cation ATPases in some rat tissues.
AS is a water-soluble hemisuccinate derivative of dihydroartemisinin, and also possesses anti-cancer, anti-angiogenesis and anti-inflammatory activities in human rheumatoid arthritis fibroblast-like synoviocytes (Lai HC, et al, 2014; Wang Z, et al, 2012; Wang HY, et al, 2014.) In our previous experiments, we found AS could protect sepsis model mice challenged with a heat-killed E.