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References in periodicals archive ?
Many studies have shown that some dihydrochalcone glycosides are natural low-calorie sweeteners, such as the phlorizin, trilobatin, 3-hydroxy-phlorizin, and so on.
The assertion is supported by the chromatographic analysis of apples, which reveals a massive account of polyphenolic compounds such as (-)-epicatechin (flavan-3-ols or flavanols), phloridzin (dihydrochalcone glycosides), (+)-catechin, quercetin (flavanols), cyaniding (anthocyanins), chlorogenic acid (phenolic acids), cyanidin-3-O-galactoside (anthocyanins), and hydroxycinnamates (p-coumaric acid) [26, 27].
Fu et al., "Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice," International Immunopharmacology, vol.
The researchers did find direct associations between dietary flavone intake and fecal levels of Blautia, flavanone intake and Lactobacillus, and dihydrochalcone intake and Bifidobacterium levels in the SLE group but not in the control.
In the present study, the only compounds identified as chalcone and dihydrochalcone, naringenin chalcone (m/z 271) and phloretin dihexoside (m/z 597), respectively, followed common pattern of changes.
Studies have found that the total flavonoids from Oxytropis falcata Bunge are mainly composed of flavonoid glycoside, flavanone, flavonols, chalcone, dihydrochalcone, flavanones, and isoflavane and have strong anti-inflammatory and antioxidant effects [27].
The most worldwide consumed sweeteners are aspartame (ASP), sucralose (SUC), acesulfame (ACS), saccharin (SAC), cyclamate (CYC), neotame (NEO), alitame (ALI), and neohesperidin dihydrochalcone (NHDC) [3].
The most abundant flavonoid in rooibos tea (Aspalathus linearis) is aspalathin, a dihydrochalcone C-glycoside.
Intraspecific variability of dihydrochalcone, chromenes and benzoic acid derivatives in leaves of Piper aduncum L.
Li, "Discovery of dihydrochalcone as potential lead for Alzheimer's disease: in silico and in vitro study," PLoS ONE, vol.
The compounds have been divided into two major classes: isoprenoids [like diterpenoids and triterpenoids containing protomeliacins limonoids azadirone and its derivatives gedunin and its derivatives vilasinin type of compounds and C-secomeliacins such asnimbin salanin and azadirachtin] and non-isoprenoidswhich are proteins/amino acids and carbohydrates [polysaccharides] sulphurous compounds polyphenolics such as flavonoids and their glycosides dihydrochalcone coumarin and tannins aliphatic compounds etc.
These results could be explained by the fact that apple leaves accumulate high amounts of phloridzin, belonging to the dihydrochalcone class [3, 16], which possesses a lower antioxidant activity than the phenolic compounds belonging to other classes [4, 45].