Thus, the main goal of our study was to evaluate the role of US/SE itself and in comparison to E-MRI in the differentiation of fibrotic and edematous pattern of CD.
A strength of our evaluation is surely the performance of SE soon after E-MRI, and thus the effect of the spasmolytic agent may have helped in the evaluation of the bowel wall and mesentery stiffness.
Abbreviations CD: Crohn's disease US: Ultrasonography SE: Strain Elastography DWI: Diffusion-weighted imaging ADC: Apparent diffusion coefficient E-MRI: Enterography Magnetic Resonance Imaging.
In another, involving 53 patients with RA, 25 with arthralgia, and 25 with other rheumatic diseases, e-MRI detected 496 erosions, compared with 379 for whole-body MRI.
A third study, involving 37 patients with RA and 28 normal patients, determined that e-MRI had a 94% sensitivity, 93% specificity, and a 94% accuracy, compared with whole-body MRI in detecting erosions (Ann.
In detecting synovitis, the study findings indicated a 90% sensitivity, a 96% specificity, and a 94% accuracy for e-MRI. But the investigators used gadolinium as a contrast agent, something few office-based rheumatologists are equipped to do.
E-MRI doesn't do as well in the detection of bone edema.
Several studies show that intra- and interrater reliability for e-MRI ranged from good to very good, but the studies all used experienced readers.
E-MRI also performs well on sensitivity to erosion change--with one study, as yet unpublished, showing that e-MRI has more than twice the sensitivity to change than x-rays alone.