E4orf4Early Region 4 Open Reading Frame 4 (protein)
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announced today that their novel E4orf4 viral death protein was shown to selectively induce apoptosis (the natural process of cell death) in several types of cancer cells in vitro and significantly retard tumor growth in mice.
Our research into the E4orf4 viral death protein and its role in promoting apoptosis provides us with encouraging information for the development of apoptosis-based cancer therapeutics," said Dan Giampuzzi, President and CEO of Gemin X.
These observations suggest E4orf4 gene therapy represents a novel caspase-independent apoptosis mechanism.