Diagnosis of EBMD is aided by taking a thorough history and undertaking a detailed slit lamp examination to identify the hallmark signs and symptoms.
The pathophysiologic hallmark of EBMD is an abnormality in the formation and maintenance of the epithelial basement membrane adhesion complex of the corneal epithelium and desquamated epithelial cells.
Successful treatment of EBMD relies upon enhancing conditions necessary for the formation of stable epithelial basement membrane adhesion complexes throughout the cornea.
35) Dystrophies which can be associated with RCES are EBMD, Reis-Biicklers', lattice and granular.
Table 1 Indications for PTK Epithelial Recurrent corneal erosions (see Figure 3, page 69), band-shaped keratopathy, bullous keratopathy, persistent epithelial defects Corneal dystrophies EBMD
(see Figure 1), Reis-Bucklers, granular, lattice, Schnyder crystalline stromal dystrophy (see Figure 2, page 68), recurrence of dystrophy on graft after Keratoplasty Superficial corneal scars Post-traumatic, post-surgical, post-bacterial keratitis Irregular corneal surface Salzmann's nodular degeneration, post-pterygium removal, band keratopathy, proud nebulae in keratoconus