EGME will support Eos Petro in bringing the Texas and Illinois assets to full production, and in further developing the company's E&P activities.
EGME pursues growth through the acquisition of underdeveloped assets at competitive valuations.
The primary metabolite of EGME is methoxyacetic acid (MAA), a short-chain fatty acid that inhibits histone deacetylase activity and alters gene expression.
Given the established role of the ER in normal reproductive function, the effects of MAA on the endogenous ER reported here are consistent with the reproductive abnormalities observed after EGME exposure and suggest that these toxicities may be due, at least in part, to attenuation of endogenous ER-mediated signaling.
Interest in EGME and MAA stems from epidemiologic analyses and laboratory studies that have linked exposure to these compounds with reproductive toxicity.
EGME exposure is associated with reproductive toxicity in both humans and animals, and the majority of these effects are attributed to MAA, the primary metabolite of EGME.