Results: We identified 34 AAV patients (21 males: 13 females; 31 Saudis: 3 non-Saudis) comprising of 23 GPA, 2 MPA and 9 EGPA
"The expanded indication of Nucala meets a critical, unmet need for EGPA
There are few cases of EGPA
reported in literature where EGPA
has been associated with multiple dermatological manifestations, commonest being erythematous macularpapular rash.
Although much energy goes into the proper pathologic classification of patients with AAV, the reality is that active AAV is treated similarly regardless of whether it is MPA, GPA, or EGPA
. The noncommittal pathologic diagnoses of pauci-immune glomerulonephritis and DAH in the kidney and lung, respectively, are evidence of this fact.
Based on the above clinical, laboratory, and imaging findings, a diagnosis of EGPA
Eosinophilic granulomatosis with polyangiitis (EGPA
) is an autoimmune disorder characterized by necrotizing eosinophilic vasculitis of medium and small sized blood vessels.1 It is a multi-system disorder involving the respiratory, cardiovascular, gastro intestinal, nervous systems and the skin.2 The diagnosis is based on the American College of Rheumatology (ACR) criteria which has a sensitivity of 85% and a specificity of 99.7% when 4 or more of the following six criteria are met ; presence of asthma , blood eosinophilia , mono or polyneuropathies , non-fixed pulmonary infiltrates, paranasal sinus abnormalities and demonstration of extravascular eosinophils in a biopsy specimen.2
He added that this qualitative conference, which is organized, in partnership between European Group for the Public Administration (EGPA
), Aix-Marseille University, the Middle East and North Africa Public Administration Research (MENAPAR) network, attracts since its launching in 2008 a prestigious elite of public administration experts from Asia, Europe and Africa.
Among patients with granulomatosis with polyangiitis (GPA) or eosinophilic granulomatosis with polyangiitis (EGPA
), the presence of skin lesions approximately doubled the likelihood of renal, pulmonary, neurologic, or other severe systemic manifestations of ANCA-associated vasculitis (hazard ratios, 2.0; P less than .03).
Muscat, Oct 24 (ONA) The Sultanate, represented by the Institute of Public Administration (IPA), will host tomorrow (Tuesday) a joint conference between the European Group for the Public Administration (EGPA
), Aix-Marseille University, the Middle East and North Africa Public Administration Research (MENAPAR) network, The Sultanate's IPA, the Institute of Public Administration (IPA) in the Kingdom of Bahrain.
The conference is a joint initiative of the Aix Marseille University (AMU), European Group for Public Administration (EGPA
) and Middle East and North Africa Public Administration Research (MENAPAR), and is co-organised by the AMU, the Institute of Public Administration (IPA), Sultanate of Oman, and the BIPA, Bahrain.
AstraZeneca Plc (LON:AZN), a global, science-led biopharmaceutical company, announced on Monday the grant by the US Food and Drug Administration (FDA) of Orphan Drug Designation (ODD) for Fasenra (benralizumab) for the treatment of Eosinophilic Granulomatosis with Polyangiitis (EGPA