EHV-1Equine Herpes Virus Type-1
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Several Burchell's zebras that were apparently healthy and later determined to be seropositive for EHV-1 were housed in the same pen as the giraffe.
We used PCR to amplify a part of the gB gene of the giraffe herpesvirus, and we used EHV-1 specific primers for sequencing.
Thus, the fact that the zebras were apparently healthy and seropositive for EHV-1 raises the possibility that the virus was reactivated and shed by one of the zebras, resulting in systemic infection and disease in the giraffe (5).
EHV-1, adenovirus, chlamydiae, rickettsiae, rabies, paramyxovirus, and West Nile virus) were negative in the polar bear, zebras, and onager.
One clade included EHV-9, EHV-1, and EHV-4 and was paraphyletic to herpesviruses from primates; the other clade comprised equid herpesviruses and a hyena herpesvirus that branched separately from other viruses (Figure 2).
In addition to finding active infection with EHV-9 in the zebras, the nature of the lesions and association of disease with compromised immunity and a perinatal animal emulated the host-pathogen dynamics of EHV-1 in domestic horses (13).
EHV-1 is endemic in domestic horses and can cause pneumonia, myeloencephalitis, and abortion (13).