Lenfoma alt tiplerine bakildiginda 20 olguda ekstranodal marjinal zon (EMZL
, MALT lenfoma), 2 olguda kucuk lenfositik, iki olguda diffuz buyuk hucreli lenfoma (DLBCL) , bir olguda mantle cell, bir olguda follikuler lenfoma saptandi.
examined the immunolocalization of VAP-1 in pyogenic granuloma and extranodal marginal zone B-cell lymphoma (EMZL) as common human conjunctival tumors.
These data suggest that VAP-1 contributes to the development of conjunctival EMZL. Since tumor cells utilize the catalytic activity of VAP-1 to recruit myeloid cells into tumors, and to support tumor progression, small-molecule VAP-1 inhibitors could be an effective immunotherapy for the inhibition of tumor progression .