ERCC1Excision Repair Cross-Complementation Group 1
ERCC1Excision-Repair, Complementing Defective, in Chinese Hamster, 1
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In this issue of the Turkish Journal of Gastroenterology, the authors investigated the phenotypic relationship of polymorphism or mutation of nucleotide substitutions determined by DNA sequence analysis in the XRCC1 and ERCC1 genes belonging to BER and NER families of DNA repair genes in gastric cancer patients.
Effects of excision repair cross-complementation group 1 (ERCC1) single nucleotide polymorphisms on the prognosis of non-small cell lung cancer patients.
In addition, EGFR can also modulate positively ERCC1 expression in prostate cancer cell lines (15) and physically interact with ERCC1 (16), suggesting a new role for EGFR in DNA repair independent of DNA-PK.
Hager et al., "ERCC1, MLH1, MSH2, MSH6, and [beta]iII-tubulin: Resistance proteins associated with response and outcome to platinum-based chemotherapy in malignant pleural mesothelioma," Clinical Lung Cancer, vol.
Xeroderma pigmentosum group F-complementingprotein (XPF) is the catalytic component of the ERCC1 structurespecific DNA repair endonuclease complex [18].
Cluster 7 included genes related to cell cycle (CCNG1; ERCC1) and cellular growth (IGFBP4; IGFBP7).
Zuiderveen Borgesius et al., "Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice," Acta Neuropathologica, vol.
The expression of ERCC1, RRM1, and BRCA1 in breast cancer according to the immunohistochemical phenotypes.
Tanshinone IIA acts via p38 MAPK to induce apoptosis and the down-regulation of ERCC1 and lung-resistance protein in cisplatin-resistant ovarian cancer cells.
Compared to the genomes of other creatures, the researchers found that bowhead whales have unique alterations in a gene called ERCC1, which is involved in repairing damaged DNA.
Objective: Several previous studies have reported the role variant of ERCC1 rs3212986 and ERCC2 rs13181 polymorphisms in the risk of glioma but the results of these studies are inconsistent.