The results showed induction of EROD
activity at concentrations > [10.
BP exposure caused the EROD
levels to double, when compared with the unexposed controls.
The study data show that maximum EROD
activity on the Sponceram was 2.
In previous analysis, both RT-PCR and EROD
activity were used as markers of activity within the liver.
MFO was then determined in the fish liver cells by measuring the EROD
In view of the equal or greater orientation of the 1990 CRP to water quality protection, which is not always geographically correlated with soil conservation, the lack of strong positive correlation between EROD
and CRP90 is not surprising.
It has been reported that EROD
activity is the catalytic monitor of CYP1A1 since CYP1A1 preferentially metabolises ethoxyresorufin into resorufin [42, 43].
Gonad size, liver size, hepatic EROD
activity and plasma sex steroid levels in white sucker.
Tanshinone IIA selectively inhibited CYPlA-catalysed EROD
and MROD activities in rat liver microsomes, without affecting other P450-catalysed oxidations such as benzo(a)pyrene, tolbutamide, chlorzoxazone and nifedipine, which are substrates for CYP2E1, 2C and 3A (Ueng et al.
We used tissue and plasma concentrations to determine dose-response relationships of hepatic EROD
activity and gene expression of Cyp1a1, 1b1, and 1a2 in liver and PBLs [see Supplemental Material, Figure S1 (http:// dx.
We measured CYP1A activity using the in vitro EROD
assay in larval microsomes as described by Willett et al.
It has been demonstrated that both the commercial mixtures and BDE-47 congener induced phase I EROD
(ethoxyresorufin-O-deethylase) and PROD (pentoxyresorufin-O-deethylase) and phase II metabolic enzyme activity (uridinediphosphate-glucuronosyltransferase) (Carlson 1980; Hallgren and Darnerud 1998; von Meyerinck et al.