ESEMS

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Environmental scanning electron microscopes (ESEM), developed to observe samples at high resolution while relaxing many constraints on sample environment imposed by conventional scanning electron microscopes (SEM), provide pharmaceutical manufacturers the ability to gather detailed information about particle size and shape from source material and drug compounds.
ESEM relaxes these requirements and provides an attractive alternative for particle size and shape analysis when developing new methods or interpreting light scattering data to control existing processes.
Figures 1-4 illustrate the application of ESEM to pharmaceutical particle analysis.
In this analysis the sample material is diluted and filtered, and the filters are introduced directly into the ESEM sample chamber.
The field of view is dependent on the particle size and image resolution, which is, in turn, dependent on the ESEM operating conditions selected for the analysis.
Figure 4, comparing the results of ESEM and light scattering, demonstrates the kind of bias that can be introduced by particle shape in light scattering measurements.
March 01 2012 (TUR) -- The top 10 shares in terms of value gained and lost on daily-basis on Thursday at the Istanbul Stock Exchange (ISE) are as follows: SHARES INCREASE% 01 - OSMENY 21.00 02 - YKFIN 15.49 03 - NUGYO 14.52 04 - ESEMS 10.38 05 - EGEEN 9.13 06 - NETAS 6.78 07 - KAPLM 6.65 08 - DMSAS 6.57 09 - IHLAS 6.00 10 - KPHOL 5.45 SHARES DECREASE% 01 - ARENA -10.22 02 - ARMDA -7.73 03 - VANGD -7.42 04 - EMKELR -7.41 05 - METAL -4.93 06 - METRO -4.82 07 - KONYA -4.59 08 - DENCM -3.85 09 - GEREL -3.31 10 - MEPET -3.26
February 23 2012 (TUR) -- The top 10 shares in terms of value gained and lost on daily-basis on Thursday at the Istanbul Stock Exchange (ISE) are as follows: SHARES INCREASE% 01 - KNFRT 17.41 02 - AVOD 15.73 03 - BURCE 9.87 04 - OZGYO 9.78 05 - VAKFN 5.29 06 - FENER 5.29 07 - TCRYO 4.84 08 - VKGYO 4.59 09 - FRIGO 4.08 10 - GNTRA 3.95 SHARES DECREASE% 01 - EMKELR -10.94 02 - KPHOL -10.45 03 - ESEMS -10.30 04 - DARDL -10.23 05 - BISAS -9.29 06 - PTOFS -5.71 07 - YKBNK -5.71 08 - DOBUR -5.63 09 - MANGO -5.06 10 - MEMS1 -5.00
February 17 2012 (TUR) -- The top 10 shares in terms of value gained and lost on daily-basis on Friday at the Istanbul Stock Exchange (ISE) are as follows: SHARES CHANGE(%) 01 - BMEKS 11,52 02 - KNFRT 10,41 03 - USAK 9,31 04 - DOHOL 8,33 05 - ASLAN 8,02 06 - KATMR 7,74 07 - PARSN 7,72 08 - TEKTU 7,69 09 - UCAK 6,92 10 - ADNAC 6,82 SHARES CHANGE(%) 01 - ESEMS -8,81 02 - CEYLN -8,11 03 - GEDIZ -6,05 04 - BROVA -3,41 05 - DENTA -3,30 06 - KARKM -2,02 07 - MZHLD -1,82 08 - ARMDA -1,68 09 - IDAS -1,47 10 - YATAS -1,47