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EUS-FNAEndoscopic Ultrasound-Guided Fine Needle Aspiration Biopsy
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Therefore, although there is a risk of tumor seeding, EUS-FNA should be considered an important modality for pathological diagnoses for small pancreatic masses.
(7,8) In the past 2 decades several studies have shown how the analysis of KRAS mutations of pancreatic lesions improves diagnostic accuracy and is particularly useful in those cases where EUS-FNA cytology is inconclusive.
The best cut-off value was selected by comparing diagnosis made by elasticity score, SR, and final diagnosis obtained by the cytopathological examination of the EUS-FNA samples or after surgical excision using the receiver operating characteristic (ROC) curve and was used to calculate the diagnostic value.
Colaiacovo et al., "Mo1414 EUS-FNA of Solid Pancreatic Lesions: a Prospective, Randomized, Single Blinded, Comparative Study Using the 22-Gauge EchoTip[R]Procoretm HD and the 22-Gauge EchoTip[R] Ultra HD Endoscopic Ultrasound Needles," Gastrointestinal Endoscopy, vol.
Preoperative percutaneous biopsies and endoscopic ultrasound-fine needle aspiration (EUS-FNA) may establish an accurate preoperative diagnosis.
Samples from C-TBNA, EBUS-TBNA, or EUS-FNA were considered "diagnostic" if specific cytomorphological abnormalities were identified by a pathologist, "indeterminate" if the pathologist identified abnormal cells but could not make a diagnosis, "negative" if normal lymphocytes were obtained, and "nonrepresentative" if no lymphocytes or abnormal cells could be identified.
There remain concerns that only a limited amount of tissue can be removed with EUS-FNA, thus reducing its diagnostic ability.
Collection of pancreatic juice during ERCP is technically easier than EUS-FNA. However, there was one drawback to the analysis of pancreatic juice.
EUS is the most sensitive and specific investigation to identify peripancreatic masses and the American Joint Commission on cancer now recommends EUS-FNA as the preferred diagnostic modality for such lesions.
reported that unnecessary surgical resection of epidermoid cyst in intrapancreatic accessory spleen can be avoided by diagnosis of this lesion with endoscopic ultrasound guided fine needle aspiration (EUS-FNA).
(3) In some instances, EUS-FNA is required to differentiate between the benign lipoma and neoplastic lesions, especially lipomatous malignancies.