EVH1

AcronymDefinition
EVH1Enabled/VASP (Vasodilator-Stimulated Phosphoprotein) Homology 1
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References in periodicals archive ?
Sprouty-related proteins (SPREDs) with EVH1 (enabled/vasodilator-stimulated phosphoprotein homology 1) domain are membrane-associated suppressors of MAPK signaling, a major regulator of cellular proliferation and differentiation.
Identification of SPRED2 (Sprouty-related protein with EVH1 domain 2) as a negative regulator of the hypothalamic pituitary-adrenal axis.
Homer is a family of scaffolding proteins formed by three members with a conserved aminoterminal enabled/vasodilator-stimulated phosphoproteins homolog 1 (EVH1) domain that binds to proline-rich sequences of mGluR [267,268], inositol 1,4,5-triphosphate receptor (I[P.sub.3]R) [269], ryanodine receptors [270], transient receptor potential canonical-1 (TRPC1) ion channels [271], and Shank [272], functioning as adaptor proteins for several postsynaptic proteins [273].
Cross-talk between these two activating systems may be modulated by several cellular signals as shown recently regarding Sprouty-related protein with EVH1 domain 2 [37].